Raoul Duke and his attorney Dr. Gonzo drive a red convertible across the Mojave desert to Las Vegas with a suitcase full of drugs to cover a motorcycle race. As their consumption of drugs increases at an alarming rate, the stoned duo trash their hotel room and fear legal repercussions. Duke begins to drive back to L.A., but after an odd run-in with a cop, he returns to Sin City and continues his wild drug binge.

Johnny Depp,Benicio del Toro,Tobey Maguire,Christina Ricci,Ellen Barkin,Gary Busey,Cameron Diaz,Mark Harmon,Katherine Helmond,Michael Jeter,Penn Jillette,Craig Bierko,Lyle Lovett,Laraine Newman,Harry Dean Stanton,Tim Thomerson,Flea,Christopher Meloni,Troy Evans,Debbie Reynolds,Jenette Goldstein,Verne Troyer,Gregory Itzin,Buck Holland,Richard Riehle,Mary Gillis,Hunter S. Thompson,Richard Portnow,Steve Schirripa,Larry Cedar,Benjamin A. Van Der Veen,Alex Craig Mann,Larry Brandenburg,Michael Lee Gogin,Brian Le Baron,Michael Warwick,Tyde Kierney,Ransom Gates,Frank Romano,Gil Boccaccio,Gary Bruno,Ben Yeagar,Christopher Callen,Gale Baker,Chris Hendrie,Stephen Bridgewater,Donald Morrow,Jennifer Elise Cox,Robert Allen,David Brisbin,James O'Sullivan,Milt Tarver,Kathryn Alexander,Mia Babalis,Kristin Draudt,Trudi Forristal,Nan Friedman,Judith Lieff,Tane McClure,Diana Mehoudar,Geoffrey Nimmer,Marlene Bologna,Chobi Gyorgy,Karen Price,Lisa Hoyle,Joseph S. Griffo,Kim Flowers

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